I would think that expectations are higher for GILD. I don't expect much price action even if GILD easily beats the expectation. It would be another story if they report blow out earnings as well as rise their guidance...we'll see in a few hours. In either case I will not sell my position but keep it for the long haul.
I've maintained rather larger positions in GILD and BIIB as well. With price targets around 140 for Gilead and an outstanding quarter I'd say lightening strikes twice could be possible. I've also positions in AMGN and ALXN. It seem bio-tech in general is doing well today.