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Questcor Pharmaceuticals, Inc. (QCOR) Message Board

  • p_marette p_marette Apr 20, 2013 11:53 AM Flag

    Acthar review

    The following was found on Google:
    The use of ACTH in the diagnosis of adrenal insufficiency and in the treatment of MS exacerbations is diminishing, with cosyntropin and corticosteroids, respectively, preferred over ACTH for these uses.

    In prospective, randomized trials of ACTH or cosyntropin for the treatment of infantile spasms, between 40% and 90% of patients experienced cessation of spasms. Hypsarrhythmia, as diagnosed by EEG, resolved in 20% to 90% of patients, and relapse rates range from 14% to 33%.25 A more recent, larger, and better-designed study suggests that cessation of spasms with hormonal treatment (without distinguishing between prednisolone and cosyntropin) is likely to occur in 73% of patients.30

    According to the best available evidence, hormonal treatment (without distinguishing between prednisolone and cosyntropin) does not appear to produce significantly different developmental outcomes than vigabatrin at 14 months of follow-up. Vigabatrin has been studied extensively for patients with infantile spasms and is recommended as a first-line treatment in the United Kingdom.18 It is not available in the U.S., but phase 2 trials are under way to assess its effects on cocaine and methamphetamine addiction.28,29

    The cost of H.P. Acthar Gel increased dramatically in August 2007.9 In most situations, ACTH should be reserved for patients who have not responded to treatment or who cannot tolerate corticosteroids and cosyntropin.

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    • Yeah, okay. Google Vigabatrin and you will find that about 1/3 of the people who take it have permanent vision damage. Vision does not improve when you stop taking Vigabatrin.

      If you really need help getting Acthar do what Mikey says.

    • No I am not a shorty! I was thinking about increasing my position on QCOR but when I checked out my prescription drug list I discovered that a 34 day supply of Acthar would cost me $1345.00. My wife has MS and we have tried a number of different treatments without much success. I'm not sure I can get approval on this drug. If I cant get approval I have to believe others cannot either. So, I posted the info hoping to get some positive feedback. I guess that's not in the cards.

      • 2 Replies to p_marette
      • Just in case you aren't a short, and are actually on a stock investing board seeking advice on how to obtain insurance coverage for a drug you need, then

        Go to Questcor's website as they have not only a phone number you can call for people to help you get coverage but also an assistance plan to help poor people (free drugs) and co-pay assistance.

        Check with your doctor and insurance company to see if he can bill Acthar through your medical insurance (as opposed to your pharmacy benefits). If so, then it's part of your annual deductible which you will probably meet anyways each year, if you have MS. UPMC and some other insurers allow this, if your doctor is administering it.

        Now keep in mind, my eyes were rolling the entire time I typed this helpful message because YOU ARE ON A STOCK INVESTING BOARD seeking medical and insurance advice. You did this by not even asking a question, but rather posting some garbage.

        So, I'm not buying your story. No one else is either. However, on the off chance you are that stupid and really are looking for help. READ THIS MESSAGE AGAIN!

      • I am having great difficulty following your twisted logic. You state " I'm not sure I can get approval on this drug. If I cant get approval I have to believe others cannot either".
        This is what I think I see in your statement, since I don't know if I can get approval, and I have not checked or I would know the answer to that question, I assume that everyone else out there( who has the same question as I do) is just a stupid as I am and therefore since I don't know the answer to said question, others cannot get approval either.

        Well, I think the answer is that all insurance companies will approve its use if the cheaper drugs do not work. But, I don't know what insurance company you have. You could be insured by the Acme Insurance Co., you know, the one the road runner uses.


    • UK doesn't mind side effects as opposed to cost. They will risk even death with thier socialized medicine.

      Synacthen has benzyl alcohol (or so prop think says) which causes something called gasping syndrome. Not FDA approved because of it.

      Cosyntropin is a powder and must be titrated IV. Cheaper costs supposedly offset by increased costs in care. Someone here did a write up on that a long time ago.

      Vigabatrin took 9 years just to get approved, but no one will use it. You shorts think Aetna policy says bad things about Acthar. One insurance company conclusion below but even worse are found if you Google it. This is just the first one that pops up!

      "No conclusions about the efficacy of vigabatrin (Sabril) can be drawn from the poor quality trials critiqued for this review."

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