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Questcor Pharmaceuticals, Inc. (QCOR) Message Board

  • pharmaman58 pharmaman58 Aug 22, 2013 7:59 AM Flag

    lupus,nothing new here but putting pieces together

    1. New trial alert from mikey.
    2. Efficacy end points met in trial with challenged patients where steroids did squat (n=7).
    2. On label indication for a subset of lupus patients.
    3. Layers into existing rheumatology and neurology sales forces.
    4. Provides entry into dermatology market.
    5. Huge population.
    6. The only treatments are
    --BenLysta--first new drug for lupus in 50 years, effective for less than half of patients, but better than nothing.
    --a couple of experimental MABs (mixed results)
    --mycophenalate mofetil and other immunosuppressives: in other words, the same drugs that are hauled out for many autoimmune and inflammatory disorders because there ain't nothing else (IMO). These drugs suppress the immune system which may alleviate lupus symptoms but may also cause a wide range of other problems.

    A primer for anyone interested: wwwDOTcdcDOTgov/arthritis/basics/lupusDOThtm. Or go to the Lupus Foundation of America web site.

    I'm adding up a big, big potential win here. How big? My thought: a few hundred scripts in 2014, 1,000 scripts by 2015. Number of vials per script could vary depending on patient situation--for flares, maybe 2 vials, for lupus nephritis, 3-4 vials (guesswork here).

    Sentiment: Strong Buy

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