"Acthar’s label (revised in 2012), by which it gains grandfathered permission from the FDA to sell
Acthar in the United States, states it has one active ingredient: Corticotropin, or purified ACTH."
Answer: Note that 'purified ACTH' is stressed by putting it in bold and also tweeting it here and there. He claims the prescribing information says that's what Acthar is. Guess what, the PI doesn't say that, and if it did, that would be a lie for any biologic. He links to the PI right in that sentence, claims it says that, and it doesn't.
What does it say? It says that it is a highly purified sterile preparation.
Am I mincing his words, or is the accuser mincing theirs?
Well to answer that, lets focus on two things. First, it also states it is an ACTH analogue. It doesn't state it is just a polypeptide chain of 39 amino acids. It says analogue. Now anyone who has taken biology, chemistry, or other classes understands that an analogue is not the same as what you are comparing it to. It's similar! FDA and the Controlled Substance Act have definitions that cover that word also.
By putting the word purified in front of ACTH instead of keeping it where it is in the document, effectively you've changed the meaning from, " hey we got this biologic that needs to be purified to get rid of any potential foreign substances, diseases (like madcow back in the old days), and other stuff" to accusing them of saying they somehow "extract only polypeptide chains of 39 amino acids without breaking any of the chains, except of course, the other chains like a B-Growth hormone and other stuff that is usually attached to ACTH in a biologic system (read that as your pituitary glands)."
Why is this important? Well, by using the brain and educational power of a 5th grader, the accuser is mixing terminology to suite a particular need. Take this word from that sentence, add it to another sentence, leave out these 5 words... viola!
I never understand the posters who do not like apple, yet they feel compelled to post on the Apple board. Really strange to me?! After I sell a stock, I do not go back the stock board to post stupid inane messages. Weird! Check out Underground Stock Alerts (google them), made $25k on their last alert PLUG