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SciClone Pharmaceuticals, Inc. Message Board

  • usualsuspect9753 usualsuspect9753 Apr 4, 2007 6:42 AM Flag

    survival on 22 patients

    Is Sciclone next?

    Cell Genesys Shares Jump on Study Data
    Tuesday April 3, 4:24 pm ET
    Cell Genesys Stock Surges on Positive Follow Up Data for Prostate Cancer Drug Candidate

    NEW YORK (AP) -- Shares of biotechnology company Cell Genesys Inc. jumped Tuesday on positive follow-up data from the company's prostate cancer drug candidate.
    The stock gained $1.39, or 32.3 percent, to close at $5.70 on the Nasdaq Stock Market. Shares have traded between $2.77 and $8.10 over the last 52 weeks. Volume Tuesday neared 60.3 million shares, more than 58 times its normal trade.

    The company said follow-up data from a mid stage clinical trial of GVAX showed patients survived longer. Cell Genesys is using the same dosage in its ongoing late-stage study of the drug.

    JP Morgan analyst Richard Smith reaffirmed a "Neutral" rating on the stock citing the data and said the company is a longer term play, with Phase III clinical trial data expected in late 2008.

    "In the meantime, we see close management of expenses as necessary to reach the goal line," he wrote in a note to investors.

    Cell Genesys was also given a boost by the recent Food and Drug Administration panel endorsement of Dendreon Corp.'s prostate cancer vaccine Provenge, he said. The FDA is expected to make a decision on whether to approve that drug May 15.

    Meanwhile, Canaccord Adams analyst Joseph Pantginis reaffirmed a "Buy" rating with a $7 price target, also citing Dendreon's good news.

    The data update from Cell Genesys can also help the company in its partnering discussions, he wrote in a note to investors.

    "We view this GVAX prostate survival update as a strong incremental positive for Cell Genesys that further solidifies our projection that GVAX Prostate will play an integral role in the treatment of prostate cancer," he wrote.

    Some on Wall Street urged caution, however. Lehman Brothers analyst Jim Birchenough noted that the study showed promising results compared to the current standard of treatment, but added that the small number of patients involved and other issues may have biased the results. He pointed to a number of Phase II studies that showed positive results that didn't pan out under further testing. "Indeed with only 22 patients as a basis for GVAX analysis and no way to control for patient selection bias, we believe that GVAX survival data is more likely driven by better patient baseline status than specific drug effect," he wrote.

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    • today Jesus rised from the dead tomorrow SCLN

    • Pfft, my wife's nick, my apologies. It's late. Tc

    • >>>I thought Jesus's disciples went back to their villages and resumed their earlier lives immediately after the death of Christ. I thought the only people at the tomb of Jesus were Mary and Mary Magdalen.<<<

      The Bible says the two Marys and another woman, Salome, were there 1st. They saw that the stone had been rolled away and went and got Peter and John to come see what had happened, and they did. Peter and a few of the other disciples went fishing (Peter was a fisherman) a few days after Jesus was crucified, but Jesus appeared to them, they touched Him and ate with Him, He told them to make disciples of all the nations, etc (read the last two chapters of John and the last chapter of Matthew for the specifics). Afterwards they preached Jesus to the point of matryrdom. My church did an awesome Easter service, and in one of the closing songs, "Leave a Legacy," the fates of the 11 disciples (when they were martyred and where) were posted up on the video screen. From memory, Nathaniel was whipped to death in Armenia in 70AD, James the Greater was beheaded in Judea in 44AD, Philip was stoned to death in Phrygia in 66AD, Peter was crucified upside down somewhere in 74AD, another disciple was speared to death in India, Simon the Zealot was crucified in England...pfft, I don't remember the others, and I may even have details of the ones I listed wrong, but the point is that they all died preaching the gospel except for maybe John. The book of Acts mentions Philip, James, and Peter and maybe others (bedtime here, can't rememeber offhand). If the fate history records for the disciples is accurate, they must have believed that Jesus had, indeed, risen (why spend and end your life based on an untruth? What would have been in it for them?) And so, if you disbelieve that Jesus was the Son of God, you have to explain away the fate of His disciples somehow, because, clearly, THEY believed. Tc

    • I thought Jesus's disciples went back to their villages and resumed their earlier lives immediately after the death of Christ. I thought the only people at the tomb of Jesus were Mary and Mary Magdalen.

    • Atheism isn't a religion. Religious symbols on govt property has nothing to do with Atheism only about seperation of Church and state. Some people (framers of constitution) are sensitive to mixing both. " atheism is simply an admission of the obvious" Harris. This duology could go on for months (already thousands of years) so it seems empty as I'm only looking for evidence which presently doesn't exist. It may exist in 10-20 years then my beliefs will evolve.

    • Now it is back to Scln. I don't have much faith but reasonable amount of shares.

    • If man does not abide in me he is cast forth as a branch and withers; and the branches are gathered, thrown into the fire and burned. John 15:6 (Was this the justification for burning heretics alive?)

      If a man discovers on his wedding night that his bride is not a virgin, he must stone her to death on her father's doorstep' Deuteronomy 22:13-21 (MUST not may)

      God deems it just to repay with affliction those who afflict you...when the Lord Jesus is revealed from heaven with his mighty angels in flaming fire, inflicting vengeance upon those who do not know God and upon those who do not obey the Gospel of our Lord Jesus. They shall suffer the punishment of eternal destruction and exclusion from the presence of the Lord and from the Glory of his might...
      Thessalonians 1:6-9

      Today's NYTimes magazine had an interesting article about Pope Benedict and Western Europe's secularism. Two books written by Pope Benedict from 2004 and 2006 sound interesting so I ordered them on Amazon. My mind is still open.

    • Do gay people go to heaven? Can a person who commits suicide go to heaven? (mental illness). Did Noah gather two fire ants for the Ark? Yes or No, per the Bible.

    • "Religion isn't about tolernce and acceptance of other beliefs."

      Atheism has its extremeists as well and thus cannot be said to be about acceptance and tolerance either. You know-- all the folks who cannot bear to see a christmas tree (which is more about social celebration than religious rite anyway), the ten commandments, or see or hear the word "God" anywhere at any time... Personally-- I classify Atheism as a religion, since it has a central belief set centered around the theses that there is no God, and that man can live morally upright lives without believing in God. Anyhow. What is your point?

      "Each holy text literall promotes murder of anyone who doesn't follow or beleive their wy"

      You are mistaken. The New Testament does not advocate a "convert or die mentality". Followers of Christ are admonished to love their enemies, and to do good to them that hate them; to turn the other cheek,.... Disciples, sent out to preach the gospel were told to leave the homes of those who rejected the teachings-- to shake the dust off their shoes.... not to execute everyone in the place... According Matthew's account of the sermon on the mount, Jesus told his followers "You have heard that it was said, "An eye for an eye and a tooth for a tooth". But I say to you, do not resist an evildoer. If anyone strikes you on the right cheek, turn to him the other also." (Matthew 5:38-39, NRSV) This is the essence of religious tolerance. Followers of Christ are obliged to follow His teachings-- or they are not followers of Christ.

      Tolerance does not mean that folks who do not ascribe to the beliefs set forth have some right to be embraced into the religious community (eg-- folks living openly gay lifestyle expecting-- demanding conservative christian denomination open doors to them for rites and positions that symbolize church endorsement). Tolerance does mean that individuals who choose to live lifestyles that are not compatable with the conduct requirements of whatever religious group are permitted to do so peacably in their own space. However, mankind, as a species, is not very tolerant of differences and seems innately driven to seek dominance, so I suspect the root of the problem is not religion per se, but the very nature of man.

    • "Religion seems like firy tales and require too many leaps of faith or with transparency and critical thought seems to be mental illness."

      Religion deals with those aspects for which science has no means of exploration. Science can describe how life works, etc... but ultimately, either one has to embrace the theory that matter and energy derived from the abject emptiness of complete nothingness-- or there is a creator who brought all that is into being.

      As far as prayer is concerned-- the experiment you cite was terminally flawed in that Christianity teaches only that God answers prayer-- not what the answer will be. Assume for a moment that Christian teachings are correct, with regard to eternity, etc... and consider for a moment a christian suffering from a terminal disease. S/he prays to God to be made well. God answers the prayer by hastening the persons death, taking the person to heaven, thus ending the person's suffering-- permanently. The person's prayer was answered-- but not in a way that can be measured in terms of this world.

      Folks who believe that the foundation of the universe-- where anything came from at the beginning-- can be described by science are suffering from a form of delusion

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