Amazing article: the drugs don't work (doesn't apply to nektar)
Search for an article 'The Drugs Don't Work' by Ben Goldacre. Absolutely amazing. Arguably, this should apply less to Nektar's drugs than to others since all Nektar is doing is improving drugs that have already been shown to work. (Having said this, after reading the article, you will lose a significant amount of confidence that anything works.) What a racket this is.