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Nektar Therapeutics Message Board

  • trigfest99 trigfest99 Sep 26, 2013 5:06 PM Flag

    Will be Oversold...

    Buying opportunity for people who understand this. Efficacy proven just as effective as standard opioids. Why when went from 181 to placebo was there not the increased pain/rebound noted in prior similar trials? Answer is bc the prior trials were un-blinded. They were un-blinded because the euphoria experienced on the drug stopped when subjects went from drug to placebo, so the subjects recorded the increased pain which really was the pain of not getting high. That is only explanation for different reaction of the placebo arm. So the reason why this trial technically failed is exactly because it does what it is supposed to do (ie;provide pain relief without the euphoria). This will climb back as this is analyzed...

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