Good and easy reading, folks. Brian's article focuses on ICT-107. I find that his style is easy to grasp.
The reason it is so important for a vaccine to target several antigens is because cancer has the ability to quickly mutate, and even if destroyed, it can come back stronger and in other parts of the body. The "one antigen approach" may work in treating the cancer, but if the cancer evolves or begins to express another antigen then a treatment becomes less effective or even ineffective if it mutates and no longer expresses the original targeted antigen. IMUC's ICT-107 targets the cancer from multiple points, and prevents it from metastasizing into other cancers of the body, therefore blocking many avenues for the cancer to evolve.