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pSivida Corp. Message Board

  • terry290737 terry290737 May 6, 2014 7:03 PM Flag

    This has been in the works. Tethadur not a drug a delivery system

    OncoSilâ„¢, the product, contains porous silicon microspheres (micro beads) mixed with phosphorus and irradiated to create phosphorus 32 (P32) containing radioactive beads. These micro beads are mixed with a proprietary suspending fluid, and injected directly into the tumour. P32 emits beta particle radiation over a few weeks, killing dividing tumour cells. The radiation only extends outwards about one half inch from the beads, so healthy tissue is spared. Once injected, the beads stay in place, and do not migrate round the body.


    Unlike most polymer-based drug delivery systems, the manufacture of Tethadur does not require complex chemistry and the final product is pure silicon irrespective of the delivery characteristics imparted by the nanostructuring process.
    Tethadur distinguishes itself from other delivery systems by its heat and radiation stability, simplifying the manufacturing and sterilization process.

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