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Advanced Medical Isotope Corporation Message Board

  • paradigmwizard paradigmwizard Feb 21, 2008 10:19 PM Flag

    Jesse Jackson to be at Grand Opening!

    This just confirmed! - Jesse Jackson will be at the ribbon cutting for ADMD's grand opening in March.

    There is a lot going on and with the addition of Jesse Jackson into the mix, and things could get very interesting. The Reverend Jackson is involved in a program to bring medical isotope technology to treating HIV/AIDS and he is also close advisor to the Democratic presidential hopeful Sen. Obama. You can bet that Isotopes will be a much wider talked about subject by the time we see a new President in the U.S.A. We will continue to see a string of news releases in regard to the new linear accelerator and new lines of business coming on line.

    Here is a piece from Scientific America and it is just what Jesse Jackson and Sen. Obama are looking to push in their agenda for bringing relief from this plague of AIDS.

    Radioactive Antibody "Missiles" Home In on HIV

    It worked for treating cancer; now researchers have found they can send dollops of lethal radiation directly into HIV-infected cells using radioactive antibodies. So far the technique only works in mice, but investigators hope they can extend their proof-of-concept to a treatment capable of destroying all of the infected cells in a person's body under some circumstances. "Twenty-five years from the start of the epidemic, HIV is still an incurable disease--something completely different needs to be done to completely eradicate it," says nuclear medicine specialist Ekaterina Dadachova of the Albert Einstein College of Medicine in New York City, first author of a report published November 6 in PLoS Medicine that describes the results.

    Antiretroviral drugs keep HIV at bay but do not kill the virus. Instead they stop it from reproducing and let the immune system clear out infected cells. Dadachova and her colleagues reasoned they could kill these cells directly and with minimal harm to the rest of the body if they could make radioactive isotopes cluster around the cells. Researchers have already found success against certain cancers by attaching radioactive isotopes to antibodies that seek out tumor cells. So the team linked radioactive bismuth 213 and rhenium 188 to antibodies designed to stick to two HIV proteins (gp41 and gp120) displayed on the surface of infected cells. To see if the antibodies would home in on the offending cells, they injected the compound into mice that contained human blood cells infected with HIV. The compound appeared to work safely: the treated mice had less than half the quantity of infected cells that their untreated counterparts did, and the animals suffered collateral damage to healthy blood cells only at the highest antibody dose, the group reports. Dadachova says the team is working with a pharmaceutical company to see if a clinical trial is warranted.

    In principle, the technique could supplement antiretroviral therapy for a brief time, especially very early in an infection before the immune response has kicked in, says AIDS vaccine researcher David Montefiori of Duke University. "This is the type of treatment technology that gives one hope it might be possible to eliminate the virus," he says. Major uncertainties remain, though. As HIV infections progress, some infected cells go dormant and do not cover themselves in the proteins, or antigens, that antibodies recognize. Treatment, let alone cure, is only possible, Montefiori says, "if this therapy is effective in killing HIV -infected cells in humans, as it was in mice, and if the latently infected cells can be induced to express viral antigens.

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    • I forgot to mention that I also just learned that the company's new linear accelerator is scheduled for delivery late this month and should be turning out medical isotopes shortly thereafter.

      Management has been having meetings all over the country lining up new facilities and new customers for a whole slew of isotopes that they will be able to produce.

      The Reverend Jackson is involved in a program to bring medical isotope technology to treating HIV/AIDS and he is also close advisor to the Democratic presidential hopeful Sen. Obama. You can bet that Isotopes will be a much wider talked about subject by the time we see a new President in the U.S.A. We will continue to see a string of news releases in regard to the new linear accelerator and new lines of business coming on line. I think we will see a very fast move up on this stock as the volume comes into ADMD.

 
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