I read the press release to say that at low doses they don't see the side effects they see at high doses and do still get the desired weight loss. P&G is a cautious old line company that very carefully guards its image. For them to be directly associated with a drug that might produce "herpes cold sores " God forbid. The mgr. that let that happen would have no career and AVON would have a field day as they did with the old P&G logo and the devil worship issue. The drug may not have the block buster revenue potential to get P&G to see past the risk. However, maybe they have left not insignificant revenue on the table for REGN to make. P&G owns 16% of REGN and wants them to be successful. This way they cut direct ties to the drug and help REGN who does not have the image issue to worry about, yet.
From the press release------------| "The multiple dose study (daily administration for 14 days) was conducted at doses that were well tolerated in the single dose part of the study. Nine patients and four placebo patients have been completed to date with no reports of nausea, vomiting, cough, or herpes cold sores. The treated patients lost weight and had decreased food (caloric) intake compared with those on placebo. ``The initial efficacy results are encouraging but need to be confirmed in our planned Phase II study, which will include more patients who will receive AXOKINE for a significantly longer period of time,'' said P. Roy Vagelos, M.D., Regeneron's Chairman of the Board."