Lilly's Cialis shows promise in muscular dystrophy, WSJ says
Eli Lilly's (LLY) erectile dysfunction treatment Cialis has shown promise in treating Becker muscular dystrophy in a small study, The Wall Street Journal reported last night. If the promise suggested by the initial human study continues in further research, it may present a potential new approach for the more common form of the disease, Duchenne muscular dystrophy, or DMD, the report noted. The Fly notes that Sarepta (SRPT) is developing a treatment for DMD.
There is zero reason to expect that Cialis would help with DMD. In the absence of dystrophin there is no chance of mechanistic recovery. Zero chance. That said the goal of exon skipping is to turn DMD pts into beckers pateints, and it is reasonable to assume that cialis may help those treated pts, who now have functional dystrophin. This goes one way only.