so did Depo. What is a "reassuring trend"? If there exist such a trend, then there will be no movement after approval. Since the higher chance of approval will have been priced in.
You are an idiot if you believe that the price actions prior to FDA decisions are any indicative of the probability of approval. What matter more is the actual drugs/product in question and any amount of other things. You should be better informed by doing DD on the company than tracking recent stock performances.
I think what happened to OREX has changed how some are playing the PDUFA's. nearly everyone thought OREX was a slam dunk, and we all know what happened. I think people are settling for lower, assured profits prior to pdufa than risking getting beat up in case pdufa comes with a surprise.
If you do not need to use animal sera to maintain mammalian cell culture used to produce biologics, you do not run into this problem. This is a problem for the industry that PLX is elegantly solving. This current NDA is a strategic POC for a platform to produce biologics using plant cells grown in hanging bags being fed salt, sugar, air, and light. Generally those are a lot cheaper and a lot less risky than sourcing things like interleukins and sera needed for CHO production lines.