Mon, Apr 21, 2014, 6:02 AM EDT - U.S. Markets open in 3 hrs 28 mins

Recent

% | $
Quotes you view appear here for quick access.

Protalix BioTherapeutics, Inc. (PLX) Message Board

  • zev101 zev101 Jun 13, 2012 2:07 PM Flag

    Question

    Is it true that the total number of Gaucher patients worldwide, is 10,000?

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • Yahoo would not let me post a reply. I think their filter finds the name of my ethnicity offensive - probably an extremely stupid way to handle the antisemitic posts popping up every now and then. I will try with just "J" instead of the full name.

      I don't really know, but http://www.gauchercare.com/en/patient/about.aspx has the number you mentioned:

      "It is estimated that approximately 1 in 40,000 to 60,000 people in the general population have Gaucher disease, or about 10,000 people worldwide. Among J's of Ashkenazi (Eastern European) descent, the incidence is higher: up to 1 in 450 people. The higher frequency of Gaucher disease among this population has led to the misconception that Gaucher disease is a "J'ish genetic disease,” but in fact, individuals of any ethnic or racial background may be affected."

      Now let's do some math. First, let's assume that:
      (1) - The world population is 7 billion,
      (2) - The incidence in the general population is 1 in 50,000, and
      (3) - The effect of Askenazi J's on the world-wide statistics is negligible (we are not aiming at high precision here).

      In that case, the probable number is 7,000,000,000 / 50,000 = 140,000

      Obviously, there is an error somewhere. Is it in assumption (2) - the incidence? Or, is that 10,000 number incorrect?

 
PLX
4.15-0.03(-0.72%)Apr 17 4:02 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.
AstraZeneca PLC
NYSEThu, Apr 17, 2014 4:00 PM EDT
KeyCorp.
NYSEThu, Apr 17, 2014 4:01 PM EDT