We're certain there's "No equivalent Therapy" like some user posted a link from FDA website.
Now this one. From wiki: "A new chemical entity (NCE), or new molecular entity (NME), is, according to the U.S. Food and Drug Administration, a drug that contains no active moiety that has been approved by the FDA in any other application submitted under section 505(b) of the Federal Food, Drug, and Cosmetic Act."
It's very simple. The hardest part it's finding that NONE drug approved has " ICOSAPENT ETHYL".