Dr.Barry Sears of Zone-Diet has been saying that for some time.
He told me that he has tried high dosage of upto 24 gram/day of EPA and 16 gram of DHA for Cancer and Alzheimer patients.
He measures AA/EPA ratio for each patient in deciding the correct dosage.
Dr.Sears told me that Reduce-It study should try 6 -8 gram/day of VASCEPA to get great reduction in Coronary events as Americans have much higher AA/EPA ratio compared to Japanese.