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Amarin Corporation plc Message Board

  • terridiamond158 terridiamond158 May 3, 2013 4:00 PM Flag

    If AMRN Drug Lowers LDL ,,Why Would Dr. Use Lovaza That Raises LDL ?

    I have this problem and my LDL count is most i,portant thing.

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • I have the same problem, my doctor just took me off Lovaza and put me on Vascepa and told me I will live 10 years longer now having higher LDL.

    • For most everyone, LDL count can go up and not be a danger. In fact, if your LDL is an actual medical problem, you are probably taking a prescibed statin to help control LDL.

      Lowering LDL is most important thingand has nothing at all to do with Vascepa. Vascepa is for adjusting extremely high trigs. Lowering trigs hasn't yet been demonstrated to the FDA to have health benefits. Reduceit study is going to try to connect lowering trigs to actual health benefits. We'll see in 4 years what they come up with.

      People with severe high trigs can now use Vascepa to lower their trigs if they want. Everyone else (for now) is told to eat better and excercise. Hopefully the 5 year reduceit study that is started now can actually show some sort of advantage regarding ce. Eventually, people with high trigs can take Vascepa. For now, people with high trigs cannot take Vascepa. Until Vascepa is an option for them, they will just continue eating better, excercising and taking pharmaceutical grade pure epa capsules to control their trigs. If that doesn't help them, then Vascepa won't help anyway because Vascepa is just pharmaceutical grade pure epa, Furthermore, pure epa is much less effective at reducing trigs than changing diet and excercise. That is why Doctors tell patients to eat better and excercise to keep trigs in control. If you have severe trig issues, then you might need additional help like pharmaceutical grade epa, etc.

      • 3 Replies to brownbrothersco
      • I think you should do a little research before speaking with such authority. Alo the FDA allows Vascepa to be used for any purpose you want. Doctors will prescribe Vascepa for any promising indication shown in a reputable study because it has no side effects.
        You might start here:
        Am J Cardiovasc Drugs. 2013 February; 13(1): 37–46.
        Icosapent Ethyl, a Pure Ethyl Ester of Eicosapentaenoic Acid: Effects on Circulating Markers of Inflammation from the MARINE and ANCHOR Studies

      • brownbrothersco I have had high cholesterol and LDL going up IS THE BIGGEST danger to get a heart attack. You are an idiot PEOPLE AT RISK OF HEART ATTACKS SHOULD JUST START EATING BETTER ???? LOVAZA MAKES YOUR LDL GO UP 45% MY DR. TOOK ME OFF IT AND TO VASCEPA SAYS GREATEST DRUG FOR PEOPLE IN RISK OF HEART ATTACK. DO YOUR FREAKIN DD IDIOT.

      • Brown
        I know more about this then I hope you will ever need to know . I've been in a clinical trial for CV drugs , had a cardiac cath to determine the extent of plaque buid up in my coronary attires , had my application to the Reduce it Trial rejected twice ( partially because they determined my life expectancy was greater then 5 yrs ).. Father died at 50 from heart attack etc etc .....like I said ...more then I hope you will ever need to know .

        So I don't want to waste a Friday night politely correcting you except to say. ... LDL levels are a straight line function of CV risk ...the higher your level the higher your risk ...period ....from those I know that publish in the field..
        You are correct in that diet and exercise is the first line of treatment and that some Cardiologist will not treat TG 's under 400 .....but after you have max'd out on diet and exercise , even if you can stay on program ...if you aren't at lipid panel goals you will need meds .....and high grade EPA or RX Vascepa is by far the easiest to take ....and I've taken practically all of them ( except Lovaza ) over the past 25 yrs
        AK

    • shorts have no clue.

    • Need to educate him

      Sentiment: Strong Buy

    • they will use AMRN drug and I also have high tri's and know LDL IS most critical part of what they want to lower.

 
AMRN
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