Alliqua, Inc. to Present Results of Two in Vitro Studies Investigating the Antimicrobial Properties of its SilverSeal Hydrogel Dressing
May 2 13
Alliqua, Inc. announced it will present the results of two in vitro studies investigating the antimicrobial properties of the company's SilverSeal(R) hydrogel dressing. Data from these studies indicate that SilverSeal may be capable of rapid and sustained efficacy in managing the occurrence of wound contamination by reducing the bioburden from multiple bacterial pathogens and by sustaining this activity for up to eight days. Complete data will be presented at the Symposium on Advanced Wound Care and Wound Healing Society (SAWC/WHS) meeting taking place May 1-5, 2013 in Denver, CO. The first study tested the bactericidal activity of SilverSeal against pathogens commonly associated with wound infections, including MRSA and VRE. SilverSeal dressings were exposed for up to 24 hours to methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis (VRE), Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. The second study measured the time during which silver ions are released from SilverSeal dressings in concentrations sufficient to provide antimicrobial activity. These findings indicate that SilverSeal delivers a sufficient, sustained concentration of silver ions to provide antimicrobial activity for up to eight days in both water and normal saline in vitro and supports a seven-day dressing change period. The above results are summarized in two posters, both of which will be on exhibit May 2-4 in the Korbel Ballroom: "Silver Ion Release from a Silver Fiber Hydrogel Wound Dressing" (abstract #LB-27), and "Bactericidal Activity of a Silver-coated Nylon Fiber Hydrogel Wound Dressing" (abstract #LB-45).