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Exelixis, Inc. Message Board

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  • erniewerner erniewerner Jan 11, 2013 8:37 PM Flag

    Zytiga (abiraterone) receives approval for early use in EU, JNJ+EXEL=$'s

    "....betting that Comet 1 (combined abi/cabo treatment) gets terminated early due to positive median overall survivor stats." There is a decent chance that Comet 1 will get an early termination. EXEL built a single interim analysis into the protocol so that in case the drug showed exceptional efficacy, the company, vis a vis its standing instructions to the Data Monitoring Committee, could terminate the trial early without jeopardizing the validity of the results.

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