Doing the Math for the Math Challenged (and Crooked Pumpers)
Population of the World is 7,095,217,980, err 7 billion, one in a million affected by HoFH equates to 7,095 persons, yasser’s source for 15,000 (no link) must be guesstimating slightly more than two HoFH cases per million (vs the FDA estimate of one)…USA GDP per capita is $49,800 (2012 est.), World GDP per capita is $12,400 (2012 est.). Based on 2009 IRS statistics roughly one in two hundred of those afflicted in the USA could afford the ANNUAL 300K prescription (if they wanted to afford it). Course the USA is more affluent than most of the rest of the world, for the sake of argument we’ll assume one in five hundred of those afflicted worldwide could if the chose afford it (in reality it’ll be far less)…assuming all of those chose juxtapid (verse the far less expensive treatments), you’d have a grand total of 30 customers.