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Pacific Biosciences of California, Inc. Message Board

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  • andyisss andyisss Jan 23, 2013 9:39 PM Flag

    This stock reminds me the story of HLCS

    Based on my count PACB has at least 30+ sequence on market and actual list might be longer. Error rate is higher then Illumina but long reads are always good. You can't assembly a genome with just 100 or 250 base pair reads due to repeats and genome complexity. There are many publications on using pacbio data for closing genomes, and more and more centers are using Pacbio to close genome.

    PacBio error rates are random (it's good because you can fix random errors based read overlap consensus) and that is due to lack of intensity discrimination during base incorporation. Pacbio already resolved lots of issues using newer algorithms ( like HGAP) and things will get better...

 
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