There is a shortage of effective treatments for cancer. I am sure patients do not care that it is a new idea or not, as long as it is prolonging their lives. I read this board often. AS/ES may be a terrific new treatment, it may only be as good as some of the other new drugs in trial. Time will tell not the constant bickering between the longs and the shorts. Neither side apprears to be willing to open their eyes. There is no shortage of controversy here. MGI-114 is already shrinking tumors in human trials. Based on what is going on with AS/ES, MGI-114 may actually be on the market before AS/ES is in human trials. I mean AS/ES not just AS or ES. This could/will be years.