IF Vical was able to use PD-1 drugs for A-7 combo in animal studies, then MERCK and BRISTOL MYERS
should have been able to use A-7 in combo with their own PD-1 drugs for their OWN animal studies.
Large companies do NOT share what they are doing in their labs with the general public for competitive reasons.
ONLY when human clinical study plans are filed with the FDA can the general public and competitors get an insight into the research pipeline of big pharma.
There is NO doubt in my mind that BMY has already done their own animal studies with A-7/PD-1 combo.. And If Merck is awake, then they should also have completed their own A-7/PD-1 studies.
While there may not be any public "buzz" about A-7, I have NO doubt that big pharma has A-7 on their radar screen, and already has completed animal studies in combo with their own systemic immune therapies.