option are priced for about a 10 dollar move either up or down. Certainly there will be volatility, but my guess is that good phase III results and a product roll out in 2015 are already priced in. If I where a large institution I would want to see some sales results before adding much more to the valuation. Could be some wild swings 5 bucks up, 8 bucks down, 5 bucks up. Just a wild guess.
Opko CEO Dr. Frost is buying Opko Shares in a huge amount. Nearly every day. Opko has outlicenced Rolapitant to Tesaro. The fee is double digit and additionally Opko will get a milestone sum (must be around 100 mio). Dr. Frost seems to expect a positive result.