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BioLineRx, Ltd. (BLRX) Message Board

  • investormdpart2 investormdpart2 Feb 4, 2013 3:18 PM Flag

    press release

    I know all about 1020 because I was an investor in Cypress. I always thought this looked promising, but the press release today clarified that all we will know in March is how many more patients will be needed to achieve statistical significance. In other words, the third party will either tell them to stay the path because it's working, to add patients because it's not working enough or to surrender because it's not working at all. That's my opinion anyway.

    Why does gaba enhancement increase cognition? Is this calming an autoreceptor or something thus stimulating dopamine release to the frontal lobes? If it's just gaba then why wouldn't a current gaba agonist work for increased cognition? I'd love to see this work, but this method of action is fairly unique.

    This downward pressure has created a buying opportunity, but I'd like to wait until the data is provided as it doesn't sound like it's going to be definitive. The only way this is a home run is if no more patients are needed. My reading of the press release is that more patients could be needed. All my opinion but it's fairly clear that this is not a a data point that is going to give a clear go/no-go.

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