Recent

% | $
Quotes you view appear here for quick access.

Corgentech, Inc. (CGTK) Message Board

  • jooo22 jooo22 Aug 27, 2005 4:39 AM Flag

    by the way, about the morons at CGTK

    I think someone on this board must love me hahaha

    He's yelling my name all the time hihihi

    JUst bought DRL again at 13.85
    Also bought ECST again at 2.15

    Still wonder why this lousy CGTK management refuse to do their jobs.

    They should hang managers like this.
    Wasting the money of investors on a drug system that already has been proven to be a HUGE disaster!!!!
    That is the reality. All the rest is hopefull wishes and will take your money away.

    BMY knew 100% the CGTK "decoy" system is worthless.
    Some guys on this board are thinking that they have more knowledge of this then BMY's best specialists!!!!

    I repeat, BMY knows, CGTK knows and many scientists know that this "system" NEVER can and never WILL work in a way that FDA would approves it.

    The work they do now at CGTK is not the work a public company should do, but a university.
    And they know that very well. They just setted up some new (cheap) trials to extend their time of existence to keep their well payed jobs!!!

    Sounds very good when people ask about your job and you can say "I am a manager of a bio company" right? Of course you keep quiet about the fact that you already know that your drug will never become successfull !!!

    That kind of people will never make it in businessland.

    What a world !!!!

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • blocking/attacking 1 protein may be enough.
      Novartis Gleevec does this for leukemia ...this one drug has annual sales of about $1.4 Billion. Link below discusses mechanism:
      http://www.gleevec.com/info/page/cml-faq
      All imo
      ------------------------------

      You are the biggest moron of all and also the biggest loser. Everytime you talk, you lose more and more money hahaha And everytime you talk, I win more and more. Last time with COOL, hahahah 17% profits in 2 days hahaha and you guy where laughing , remember loser??? hahaha
      Once a loser always a loser



      What are the side effects of Gleevec?

      The majority of patients who received Gleevec� in clinical studies did experience side effects. Most side effects were mild or moderate in severity. The most common side effects were fluid retention (swelling around the eyes, of the legs, etc.) (54%-76%), nausea (43%-73%), muscle cramps (28%-62%), vomiting (15%-58%), diarrhea (30%-57%), abnormal bleeding (19%-53%), muscle or bone pain (34%-49%), fatigue (30%-48%), rash (32%-47%), joint pain (25%-40%), headache (27%-36%), abdominal pain (23%-33%), indigestion (12%-27%), and shortness of breath (7%-21%).

      Serious and severe side effects such as low levels of certain blood cells (<1%-19%), internal bleeding (<1%-19%), water retention (<1%-11%) muscle or bone pain (2%-9%), liver problems (3%-6%), abdominal pain (1%-5%), diarrhea (1%-5%), skin blistering and rash (<1%-5%) and vomiting (<1%-4%) have also been reported in some patients. Gleevec was discontinued due to side effects in 4% of patients in chronic phase, 5% in accelerated phase, and 5% in blast crisis. There is no long-term safety data for Gleevec available. If you experience any side effects during Gleevec� therapy, contact your physician.

    • Congradulations - You've done it again !

      Every time I think you have run out of stupid things to say, you come up with something new.

      So lets see, you say:

      The CGTK mannagers are lazy and they know their drugs will never work, they are just holding on to their jobs until the cash is gone.

      Now:

      The FDA is corrupt and approves drugs that don't really help because they are
      influnenced by " BIG pharma companies".

      The $ Billion+ drug, Gleevec is no good.

      Quick! You better hurry and tell all the ill informed Doctors who prescribe it about YOUR important findings.

      Maybe you should notify the stupid managers at the $115,000,000,000.00 Novartis about the big mistake they made with Gleevec before their negligence leads to massive lawsuits that will ruin the company. I'm sure they will listen to Jooo Jooo; you know sooo sooo much about these things.

      EVERYONE please remember this is the kind of nonsense that Jooo22 posts. Don't ever listen to him and especially don't EVER make a trade based on what this dope says.

    • Yea, sure looks like a blockbuster hahaha. If you take their drug, you have a good chance to feel worse then without taking them.
      YOu also forget that BIG pharma companies HAS the power to influence FDA in their decisions !!!! CGTK managers prefere to lay down and take a nap instead of working, remember???
      LIke I said before, and this proved my case, a lot more proteins INVOLVED in deseases. So they can never create a good drug with this system !!! NEVER ! That is why so many side effect on this drug!

      There are no controlled trials in pediatric patients demonstrating a clinical benefit, such as improvement in disease-related symptoms or increased survival.
      The majority of patients who received Gleevec� in clinical studies did experience side effects. Most side effects were mild or moderate in severity. The most common side effects were fluid retention (swelling around the eyes, of the legs, etc.) (54%-76%), nausea (43%-73%), muscle cramps (28%-62%), vomiting (15%-58%), diarrhea (30%-57%), abnormal bleeding (19%-53%), muscle or bone pain (34%-49%), fatigue (30%-48%), rash (32%-47%), joint pain (25%-40%), headache (27%-36%), abdominal pain (23%-33%), indigestion (12%-27%), and shortness of breath (7%-21%).

      Serious and severe side effects such as low levels of certain blood cells (<1%-19%), internal bleeding (<1%-19%), water retention (<1%-11%) muscle or bone pain (2%-9%), liver problems (3%-6%), abdominal pain (1%-5%), diarrhea (1%-5%), skin blistering and rash (<1%-5%) and vomiting (<1%-4%) have also been reported in some patients. Gleevec was discontinued due to side effects in 4% of patients in chronic phase, 5% in accelerated phase, and 5% in blast crisis. There is no long-term safety data for Gleevec available. If you experience any side effects during Gleevec� therapy, contact your physician.

      Gleevec may affect other drugs when taken at the same time, and some drugs may affect Gleevec. In particular, Tylenol�� (acetaminophen), birth control pills (oral contraceptives), blood thinners (especially warfarin, Coumadin�+), herbal products (e.g., St. John's Wort), erythromycin, phenytoin (e.g., Dilantin��), and anticonvulsants, are all broken down by the same enzymes that metabolize Gleevec�.

    • blocking/attacking 1 protein may be enough.
      Novartis Gleevec does this for leukemia ...this one drug has annual sales of about $1.4 Billion. Link below discusses mechanism:
      http://www.gleevec.com/info/page/cml-faq
      All imo

    • Joo Joo Bee. Once again you are wrong. (But what else is new) Time is everything. The drug needs to be incorporated into the cell. Longer exposure means greater absorption. Also, it is alot easy to cut up a rat and directly observe the changes to the cells than observe heart patients and determine vein vrs arterial changes that may have or may not have taken place. Much of the CABG data was subjective.

      BTW - I don't own OVTI.

    • The previous tests only exposed the tissue in question to the drug a short period of time.
      ------------------------------

      Nothing to do with time you fool.
      It is a system! NOt a classic drug!!!!

      It works or it doesn't works. YOu seems not to understand anything about the difference between Decoy and classic drugs!!!!

      Same as you never understood why your OVTI shares arE DECREASING day after day.

      Seems you have a nose to find comp�nies with lousy managers.

      So we all are warned

    • Any thoughts on why it works in preclinical trials (ie on animals) and why it hasn't (at least not yet) on humans?
      ------------------------------
      There is not an FDA for checking out their successes on animals, right.
      And of course it works in trials in labo. Many things work there. So if you take 1 cell and 1 Decoy to block 1 protein it works.

      Can you guess how many cells your body has????

      Just like I said that scientists said, to many proteins involved in a desease. So even when they can avoid 1 bad protein to develop, there are plenty others who will do the (bad) job hahaha

      But that is not CGTK's fault. Their ONLY crime is that they know already it did not worked and it won't work. So now they use a public company to do work that should have been done in a university. There should be a law to forbid things like this.

      There job is to create DRUGS !!!!! NOt to fool around and do some labo tests.

      BMY knew 100% why they did not wanted to further invest some money in this thing, even it was small money !!!!!!

      And CGTK managers know this, otherwise they would take me to court, right?

      Like I said, 1 year ago, scientists thought that it COULD be a way to cure deseases. And now, after many failures (not only CGTK failed to deliver prove that it would work) Scientists know that it simple can not work. Not now, not later.

      Unless they find a way to command ALL proteins of a cell, witch is very unlikely they will ever can.

      Just look at their previous trial. They used a drug that would avoid some kind of residue in heart vanes with people who has that trouble.
      With their drug, their should not have been residues left compered to people without using this drug.
      Easy to see if their is still residue in vanes.
      So they failed HUGE in TWO trials .

      Means the could not block the protein or that there were more things involved then only that protein.

      Same with eczema. Many proteins are involved, not 1

      Anyway, time for the MM's to let it run. I think they still are accumulating between 2.5 - 2.6.

      Some moron putted a sell at 2.64 (3400 shares hahaha, I wonder what price he bought it) and blocks our way to 2.7

      Should have ran already,maybe even this stock too lousy for MM's as well hahaha

      Good job CGTK managers!!!! And thank you for the many press releases you gave us to keep us informed about the games you are playing in your offices.

    • Thanks for the response. Good article in
      Sept 5th Businessweek about DNA biomarkers and companies targeting specific markers with cancer being highlighted - Herceptin (Genentech), Gleevec (Novartis), Sutent (PFE), Enzatauren (LLY), Dasatinib (BMY), CP751871 (PFE).

    • GREAT POST,THANK YOU.

    • The drug is not useless. The previous tests only exposed the tissue in question to the drug a short period of time. Most likely not enough time to work. CABG test only bathed the vein in a solution of the the drug. Also it was hard to measure results accurately. New eczema trials apply the drug to the skin. The transdermal factor of skin should allow for complete tissue transfer of the drug. It can also be easily reapplied since it is topical, not the the case with CABG tests. Sometimes it takes time to find the correct application of a new drug.

      JOO22 is a wacko daytrader that believes he knows everything, but knows very little. Maybe he should start a biotech drug company. LOL!!!!!!!!!

    • View More Messages