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Isis Pharmaceuticals, Inc. Message Board

  • dinepat203 dinepat203 Nov 28, 2012 10:14 AM Flag


    GOOD TRY....

    Sentiment: Strong Buy

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    • If approved, Kynamro/mipomersen will be marketed by Sanofi’s Genzyme unit, a power play in rare diseases.

      While the FDA seems pleased with the risk/benefit profile of lomitapide for HoFH, there is always the risk of a “chemistry, manufacturing, and controls” or “CMC” issue delaying approval. Also, AEGR intends to market the drug alone in the US and EU – since the company has no commercial experience, there remains some execution risk until we see how the product launch and potential competitive positioning with mipomersen proceeds.

      Sentiment: Strong Buy

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