That was kind of what I meant. Crooke has a trust with 800K+ ISIS shares (I couldn't source this but I believe I read he has a trust with ISIS shares in it) and received $1,897,332 in total compensation for 2011 according to Forbes.
his ideas of reasonable will surly be different than a common share holder.
Poison pills are for hostile or indirect take overs. All they do is issue options to every existing share hold, except for the entity attempting a take over, and dilutes the hostile parties ownership percentage.
If an offer is made directly to the board for approval and then voted on by share holders, it would not activate the poison pill.
Think of a poison pill as a type of insurance policy. For whom it insures is debatable.