The closing bell was a tinkle. I was in the service in 1961 & I have to admit that the Isis group appeared to be on sick call. They will need more than (APC) aspirins to deliver just one viable large scale successful antisense drug. MIPO will not get it done... just the facts. Sour & the rest of the folks, Have a Great Weekend ! Yes, Vical is looking very good & outperformed Isis again this week. Shhhhh. Chuckle.