I made a lot of money with dndn in spite of the shorts goal to destroy the company, and they are still working on it(30% of the float is short now). If you know the history of dndn the shorts managed to cause a flash crash when dndn announced the results of their trial, taking out all the stop losses down to below $10 from about $25. I know this thread is OT but if you want to speculate with a stock that is less then the dndn options do some DD on INO. could be a big winner this year.
I remember that flash crash in DNDN well. But the problem with DNDN now is poor margins based on the cost of the autologous technology. After the restructuring is completed, they'll need $100 million per qtr just to break even.
Even so, big pharma will eventually make a bid, probbaly from a generic producer who wants to expand. If the bid comes, it will happen in 1H13. Probably around $8-10.
In the long run, as the medical value of autologous therapies become mainstream, someone will start a cell banking/processing enterprise with the view of driving costs down. Its a problem of logistics, scale and critical mass. Intrexon might be the one to address the problem as they have a visionary at the helm.
I, too, made a lot of money w/ dndn. I traded in and out of dndn (stock) for a few years, always to the long side. I finally struck pay dirt @ earnings in Aug, '11. Puts were extraordinarily cheap for the volatility of a biotech going into earnings. Bought 200 Aug 30 puts @ 0.29 on Aug 1 when the stock was @ $36. Earnings were reported a/h on 8/3, and the stock collapsed, opening the next day (8/4) around $12. Sold the puts for $18.35. If DNDN ever recovers, I plan to be back on the short side.