My wife has MS. So i am very aware of the costs and different therapies and their pros and cons. BG-12 is the most talked about therapy for MS patients. The shots hurt and are not as effective as BG-12. I attended a rebif sponsered dinner last month and the hottest and most talked about topic was BG-12. Patients want it badly. This drug will dominate the market like no other oral medication. Gelenia takes a ton of testing to get on and if you have to come off of it for any reason you have to begin the testing on it all over again. Real pain in the #$%$ BG-12 will dominate all MS meds in the next few years.