ot: Sarepta’s stock has shot up from a low of $2.60 a year ago to $29.82 as of Monday at 2 p.m.
Mar 4, 2013, 2:32pm EST
Sarepta reports positive pre-clinical data on Marburg virus candidate
Sarepta Therapeutics Inc. (Nasdaq: SRPT) says that in animal studies the drug it’s developing to fight a potential bioterrorism agent called Marburg virus has been shown to be as effective when injected into muscles as it is into the bloodstream.
Marburg hemorrhagic fever has no effective treatments, and has been classified as a Category A bioterrorism agent by the Centers for Disease Control and Prevention (CDC).
Sarepta, which specializes in gene-based drugs, received a $3.9 million contract from the Department of Defense in August 2012 for pre-clinical tests of AVI-7288 as administered intravenously. The contract is expected to be completed by the second half of this year, and the DoD has the option to extend it.
While the company intended to develop and commercialize its DMD drug candidate, eteplirsen, on its own, the Marburg program is being done in conjunction with the government and, if successful, would be stockpiled in case of an outbreak, the company said.
Sarepta’s stock has shot up from a low of $2.60 a year ago to $29.82 as of Monday at 2 p.m.
The monkey trial showed 83-100% survival with treatment starting up to 4 days post exposure. The incubation period for marburg is 5-21 days. It is effective, but I think the expectation would be that a marburg drug would cure an infection after symptoms appear. IThe more important aspect of SRPT biodefense drugs is that it is a platform. The ebola/marburg drugs are simply the first implementation of their PMO+ oligo RNAi platform. If the ebola/marburg drugs validate the platform it will revolutionize treatment of infections disease. Disclosure: Long 2000 shares SRPT.
oh yeah, well SIGA has 193-ST so there. and @ $4 it is considerably cheaper to buy than Sarepta. And is no where near as volitile. A year ago SIGA was @ a $1.88 so it's in a much tighter range than SRPT that just goes crazy high in the same time frame. Stick to smoken your Marlburg highs, SIGA has the best pox in the neighbourhood.