I have had CRIS a lot of times. It has been good to me. I sold CADX too soon but did quite well on it thanks to the recommendation by RET. I have IDERA and CUR, a core bought when they were in the 1-2 dollar range and a few k more shares that I trade. I have been pretty lucky so far this year, I am due for a reaming. I hope it won't be at the hands of SIGA. I expect SIGA to finally come around this year and get back to the double digits.