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Insmed Incorporated Message Board

  • bohemianclubman bohemianclubman Feb 25, 2013 10:09 AM Flag

    Just a few things...

    Regarding TB, Since it is so controlled in the States, it hasn't been on the top of my list regarding arikace developments. However, from Friday :Fri Feb 22, 2013 4:11pm EST
    (Reuters) - Los Angeles County health officials have asked for federal assistance to analyze and contain an outbreak of tuberculosis within the city's homeless population, a spokeswoman for the county agency said on Friday.

    Regarding Terry. He never really bothered me. I almost put bozo in the category of "comic relief." I knew others that liked this message board though, that simply quit checking in because they think Terry ruins the board. That said, I was outright told by a regulatory friend that the regulatory agencies don't have the time or resources to be concerned with message board posters with multiple ID's and grandiose claims of achievement, unless the poster alluded to being in a position to have insider knowledge regarding company operations. Over the weekend Terry claimed to be a 3% shareholder of another company. A 3% holder, while not required to file documents, could be perceived as having access to more company data than an average shareholder.

    I doubt if that claim will be enough to have anyone actually look at Terry's MB history, but it is worth a try. IMO.

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    • That TB outbreak is intriguing BO. I found the following -

      "Scientists have recently linked the outbreak to a tuberculosis strain that is unique to Los Angeles, with a few isolated cases outside the area.

      "This is the largest outbreak in a decade," said Jonathan Fielding, director of the Los Angeles County Department of Public Health. "We are really putting all of our resources into this."

      Health workers have identified about 4,650 people who were probably exposed and are trying to track them down for testing and treatment. Local and federal officials are particularly concerned because the cases are linked to one relatively small geographic area and one vulnerable population. But officials are concerned that the outbreak could spread beyond skid row if action isn't taken."

      The "unique to LA" would seem to suggest a strain of TB resistant to the standard four-drug treatment - i.e. precisely the public health threat mentioned in the new legislation.

      If the strain is sensitive to amikacin, Arikace would be first on the list of the drug-resistant combination therapy - if cost was not an issue. But one suspects that cost WILL be an issue given the population affected.

      p.s. We know that the NIAID knows about Arikace. They prompted Insmed to run the NTM study, and there's no reason to believe Arikace would be any less effective again amikacin-sensitive TB.

 
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