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Insmed Incorporated Message Board

  • lux19insm Aug 22, 2013 10:45 AM Flag

    For the iPlex naysayers

    lets have a serious response instead of "iPlex is dead"

    how could we have an article on muscular dystrophy on june 25th 2013 about iPlex if iPlex is dead and the stock pile of iPlex has been depleted for well over 18 months? Your probably right that insm is not actively pursuing iPlex.....but somebody is!!

    Researchers Identify Novel Therapy to Treat Muscular Dystrophy

    The research team studied the outcome of combining the following single mode treatments: increasing regeneration, by overexpressing muscle specific insulin like growth factor-1, IGF-1 and preventing cell death, by inhibiting the expression of Bax, a pro-apoptotic protein. In addition, to test the translational potential of this combination therapy, the researchers systemically treated Bax deficient dystrophic mice with recombinant human IGF-1 (IPLEX TM, manufactured by Insmed Inc).

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