Thu, Aug 28, 2014, 1:21 AM EDT - U.S. Markets open in 8 hrs 9 mins

Recent

% | $
Quotes you view appear here for quick access.

Trius Therapeutics, Inc. (TSRX) Message Board

  • mikeboasberg mikeboasberg Jul 18, 2013 7:37 PM Flag

    what do u think of cempra

    thx

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • em438@rocketmail.com em438 Jul 19, 2013 9:18 AM Flag

      To me solithromycin is a direct analog of tolithromycin (Ketek), which got pulled from the market due to Liver toxicity, I'm just having a hard time envisioning how by putting an aniline ring in the drug will fix the problem.
      there is a reason Aniline moieties are not found in drugs...look for yourself.
      Anyway, I'm not saying that this won't be a great pdufa play, it probably will be, I don't see any problems with phase 3 safety as even tolithromycin had a relatively clean clinical development profile. It was not until Tolith. was giving to the general public that it reared it ugly head.

    • one poster posted QUOTE this drug has a big old nasty aniline moiety on it...does anyone have any convincing data that this drug doesn't destroy the liver...heck put an aniline on a drug and you might as well throw a hand grenade in your liver. QUOTE

 
TSRX
13.630.00(0.00%)Sep 11 4:00 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.
TubeMogul, Inc.
NasdaqGSWed, Aug 27, 2014 4:00 PM EDT
Burger King Worldwide, Inc.
NYSEWed, Aug 27, 2014 4:00 PM EDT
Williams-Sonoma Inc.
NYSEWed, Aug 27, 2014 4:01 PM EDT