Off-label drug use is common in cancer treatment. There are many reasons for this:
Some cancer drugs are found to work against many different kinds of tumors. Chemotherapy treatments often use combinations of drugs. These combinations might include one or more drugs not approved for that disease. Also, drug combinations change over time as doctors try different ones to find out which work best. Cancer treatment is always changing and improving. Oncologists and their patients are regularly faced with few approved treatment options. Oncologists and their patients may be more willing to try off-label drugs than other medical specialties.