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Celldex Therapeutics, Inc. Message Board

  • macrocosmonaut macrocosmonaut Dec 10, 2012 10:39 AM Flag

    CLDX - are the study results correct?

    Even if the new trial results are interesting - we are talking about around 122 patients in this 2b study - and it seems to be that this study isn´t double blinded.

    In all patients there is no significant benefit to the treated patient population. Only a subgroup shows some effets - but numbers are to low in order to determine a significant statistic significance.

    So the article is falsifying when he write a p=0.008 as significant effect in 122 patient 2b study. A serious statistic needs minimum 900-1000 patients in order to determine any statistic significance.

    Such an interpretation is missleading and is questionable to show such results in bigger and mor expensive double blinded multiyear phase III trial.


    Sentiment: Sell

25.54+0.60(+2.41%)Feb 27 3:59 PMEST

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