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  • frankposting frankposting Oct 18, 2012 12:14 PM Flag

    The Smallest Big-Pharma Is a ME-TOO

    FRX's upcoming Cariprazine is also a ME-TOO antipsychotics. It is the ninth of FRX's "new nine."

    The following is an incomplete list of atypical antipsychotics:
    Second Generation
    • Clozapine (Clozaril)
    • Olanzapine (Zyprexa)
    • Risperidone (Risperdal)
    • Quetiapine (Seroquel)
    • Ziprasidone (Geodon)
    • Amisulpride (Solian)
    • Asenapine (Saphris)
    • Paliperidone (Invega)
    • Iloperidone (Fanapt)
    • Zotepine (Nipolept, Losizopilon, Lodopin, Setous)
    • Sertindole (Serdolect, and Serlect in Mexico)
    • Lurasidone (Latuda)
    Third Generation
    • Aripiprazole (Abilify)

    In which, Seroquel and Zyprexa both were blockbusters and were genericized in 2011 and 2012, respectively. Abilify still is one of the top sellers, but will be genericized in 2015.

    Therapeutically, FRX's Cariprazine is very similar to EliLilly's Zyprexa. EliLilly was fined $1.3B for illegally promotion Zyprexa. The sales of both Seroquel and Zyprexa will drop to a few $M in coming years. Abilify will follow.

    So, the fierce competition from generics will put the outlook of Cariprazine, the ME-TOO, doomy.

    You will be a loser in icompeting with cheap generics -- Solomon forgot it.

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    • Generics are so cheap!!!!

      Prozac 20 mg, Brand $7 a pill, alternative generic $0.20 a pill -- Viibryd competing with;
      Effexor 37.5 mg, Brand $5 apill, alternative generic $0.40 a pill -- levoomilnacipran will compete with.

      Zyprexa 2.5 mg, Brand $10 a pill, alternative generic 0.30 a pill -- cariprazine will compete with.

      Old man should tell his son:
      Never forget -- never compete in a field with existing generics.