Whether or not slpeen size reduced during this time period is completely irrelevant. AF is pointing and saying you didn't cross the T's and dot the i's when an illiterate just wrote an epic poem. Bottom line, the patients are alive and improving today thanks to Imetelstat, they would be ashes and buried otherwise. Spleen size will reduce gradually over time with out Jakafi. Jakafi in combination may speed the reduction, but to what end? Not like the patients are in a hurry to get back into their summer swimsuits. With the disease completely wiped out, the symptoms will, WILL dissipate. Why poison the patients with Jakafi to speed the process? No logic.
AF still remembering the days when Okarma and then the next guy running Geron ran their mouths off and never delivered to put it mildly. This trail and results from the Mayo Clinic completely different. ET can now be added to the potential market and maybe others as well.