Very clar explanation - the idea is an interesting one; hwy are you considering it; why not consider it for all the other cases too? If this person was in a trial, then it woudl be black and white - are you suggesting no trial?
Peronsally I think you may be stretching a littel bit - thats fine, but I woudl rather assuem we are in the area we best understand:
Combo or NOT? or somthing else (like your example)
Known and dismissed and not reported before? WHY?
Globe facts wrong?
This is the list we need answers for.
I hoep we get answers soon, or we will all be bitching about ELN's
I am not suggesting that the reporter got the facts mixed up on the COMBO aspect. The question I have refers to the timing of the COMBO. Now if this patient was on AVONEX when she presented with the 'exacerbated MS' (i.e. PML), and was subsequently given Tys, then we have a whole new ball game. This would still be sold as COMBO even though its obviously NOT! I would be surprised for them to administer the true COMBO upon presentation of this MS exacerbation given the knowledge that T alone was more efficious. Interestingly, the fact that she had MS suggests that she was on another treatment. What was it? Was it Avonex?
WE NEED MORE SPECIFIC INFO FROM THE COMPANIES HERE...BUT IF IT WAS AVONEX, THEN DON'T EXPECT TO HEAR ANYTHING BEFORE THE ANNOUNCEMENT OF T'S RETURN! IT WOULD KILL BIIB BIG TIME!
This Board is amazing; The facts are that most likely there is a 4th PML case under Combo therapy. Thats it, plain and simple - there is no misinformation! Either that is the truth or it is a malicious rumor. Given what BOOB said and that Globe knows its been reported to FDA means its probabaly REAL - The ony error made is to say patient died - that is incorrect form what we can tell.
Hence stock falls $1.25. Thats pretty good IMO.
So stop listening to the BS on this Board that tried to convince you there is nothing wrong - THERE is something wrong - very wrong.
BUT It may not stop T's return. It definitley increases the risk profile of the situation.
I am a long, but I must also deal with Reality. Live in Reality my friend
Best of Luck in your ELN investment
Defender...I think you are way off base here. This case is old and was discussed on this board back in May (see post 645001). She apparently wasn't on any meds but presented with PML. At the time this was thought to be an MS exacerbation so she was given Tys. You see the difference?
and it is not new - means that it will probably never be a real case
krasner wrote this from a medwatch/drugwatch filing that can be made by anybody on the FDA web site
he doesn't have any other facts