Certainly, not good news. Saying that, it shd have been expected. Testing of those WITH the ApoE4 gene, had the results been 'pos', now that would have been something! So; not good news but somewhat expected altho 'fingers-crossed' ...hoping for better news. Today the stock needs to adjust to the news and the positions of options and other trades going on w/ELN common and options. Who knows how much lower? It will get bashed but my gut says it won't (eventually) close on the day as weak as many 'shorts' had planned for. (a guess.) There still are more results forthcoming; w/better expectation. Last nite's results, altho negative, were expected. Further verbal comments are imp. I'm still 'long'. I certainly will get nicked today.