Another "possible" contributor to SHM's record volume on 4/24/03 could've been the market's rumor mill, linking Sheffield's (yet-to-be-FDA-approved) device for oral administration of spray-form pharmaceuticals to such a form of interferon, which may be the most effective treatment thus far found.
The General tried to post that information here last week, but made the mistake of NOT typing a defective hyperlink within his message and yahoo-message boards' anti-spam patrol immediately consigned his posting to cyber-space oblivion.
Rather than to try again, the General will direct those readers who are interested, to the SCRI mb.
Last Thursday and Friday (5/01 & 5/02), SCRI broke out to consecutive new 52-week highs on multiple ADVs.
Messages numbered 4643, 4646, and 4649 may explain why. While undated, the news article, 'defectively' hyprlinked in message #4643 (add the initial letter "h"), is, apparently, a post March report and might've been published around April 23rd or so, triggering the rumor mill.