Apparently Incyte is branching out into written
My personal favourite in their recent patent awards
is US patent #5,932,443: "Human antigens". In this
inspired work, sequences pulled from a lung and bladder
expression library are discussed in a fairy-tale like patent
describing the many potential applications for a sequence
that one knows NOTHING about, but can express, raise
antibodies against, use as a spread on crackers, lubricate
pistons, and could well be a better mousetrap!
scientist, I find this all objectionable and
As a human, I find it hilarious.
investor, I hope they have a policy of making new,
*applicable* patent applications once they have some clue what
the gene in question might do. I can imagine Incyte's
lawyers cringing at the prospect of defending such a
patent in court...
Overall a good article with some ups and downs
vis-a-vis Incyte. ANY pubilicity would be good now. They do
expect stock price to go up...next year! One statement
by Whitfield a bit wierd, maybe taken out of
context, talking about how Incyte management might have
even believed at one point that LifeSeq was
dead....then catches himself to say they have re-signed all
their customers etc. Could we see 30 tomorrow? expect
The number of shares that insiders have been
selling are VERY weird. 177 , 1,842 , 288 , 4 , etc. Most
of them are small and odd amounts, as if employees
are leaving and cashing out of their Stock ownership
plans or something.
Most other companies sales are
in round lots. Any explanation ?
as a scientist.
a scientist explore the
keeping an openmind is the #1 criteria of a
you should know better to make a claim you couldn't
up. Unless you are omniscient you don't know that
patents are useless.
P.S. most *scientist* take
pride in their profession.
They wouldn't brand
themselves as a generic scientist.
They would state their
For example: I am a biochemist and computer
scientist, my specialty is applying three dimensional
computer imaging software
to help other *scientists*
better understand molecular structures
and how it
affect their interaction with other molecules.
what make it *flip* ;>)
>keeping an openmind is the #1 criteria of a
I strenuously disagree. I know many open minded
lunatics, and several very effective scientists who are
very linear thinkers.
>you should know
better to make a claim you couldn't back
Unless you are omniscient you don't know that
>patents are useless.
Was something lost in the
translation? In my earlier message I expressed an *opinion*
that some of INCY's patents were so hilariously vague
and demonstrated such a total ignorance of gene
function that they would be easily superceded by a
competing claim. I don't think that requires
Perhaps you don't find the construction of a lengthy
patent around a single protein sequence and *no* idea of
gene function funny, but I think I'm entitled to my
own sense of humour. ;-) The particular patent I
referenced ("Human antigens") is full of amusing what-if
scenarios like: "Hey, maybe it's a surface marker! Maybe
it's a receptor! Maybe it does ten other things! Maybe
not! Maybe we should inhibit it! Maybe we should
upregulate it! Maybe we can use it to build space shuttles!
Maybe it'll whiten your teeth!" ;-) Funny stuff, but
not terribly scientific...
*scientist* take pride in their profession.
wouldn't brand themselves as a generic
>They would state their specialty.
isn't always necessary to explicitly state your
profession, you know. For the purposes of my discussion, it
is sufficient that I am a scientist; I think a
physicist or chemist would be equally amused by the weird
collision of patent law and genetics. If - for some
unfathomable reason - you insist that I state my credentials,
I hold a PhD in molecular genetics and am currently
post-doc'ing my way towards fame and fortune
>For example: I am a biochemist and computer
scientist, my >specialty is applying three dimensional
computer imaging >software
Ugh... you structural
guys. Years of hard work and big promises, but you
still can't predict how *any* protein will fold. ;-) I
bet we'll have cured cancer before you have a decent
thermodynamic protein model! :-)
I love dogs but this is ridiculous. Stays around
$25 give or take a few points. Can't go long or
short. These guys seem to be stretched too thin. Jack of
all trades master of none. and boy did they overpay
for Synteni. My Affx stock has tripled! Just sold
some to get in on the Curagen game. Lets see, first
management went down the tubes with Invitron, now ?????? Is
that why they put in the poison pill? Want some
management input? check out Steve Push on the GLGC board.
These guys are in the middle of what Andrew Grove
(Intel) calls an inflection point. My take: get out of
chips and more into Diadexus; thats where the money
TPADA has been very volatile lately. something is
going on here. at 7.5
cents right now, should see 20
cents again in next day or two. with
who knows how high this could go (it was trading at
little over a year ago). enjoy the ride up.
INCY should be signing up smaller biotechs to
their databases, in the coming quarters. Which will pay
higher royalty rates.... whenever that'll be.
imagine what else might drive INCY up much in the next
couple of years. It seems like the real good news is
several years away. Quarterly losses as far as the eye
Or maybe plenty of good things are going
on now and management is too busy or doesn't give a
damn about letting us know.
increasingly clear that there's better biotech investments
elsewhere. I may sell my last bit of INCY soon. If there is
major good news, then I'll get back in. It might even
be cheaper a year or two from now.
I don't know what to think regarding INCY
anymore. It is fair to guess that HGSI, AFFX, and MLNM
will outperform Incy since by any measure over the
past 8-12 months they have smoked INCY.
I used to
think that INCY had the inside track over each of those
other three, but not anymore. I am worried that the
market sees something I don't regarding INCY since I've
been long INCY for 1 1/2 years. It sure is frustrating
to watch HGSI jump, Affx rocket and MLNM march
forward while INCY lags behind.
I'm still long, but
not so strong--lately.
Any fresh INCY
Am I the only one that thinks INCY's peer group
will outpreform it? Affx in gene chips, and HGSI and
MLNM in pharmicogenomics. It seems the positive news
flow out of these already leaves INCY far behind. As
for INCY databases, will they ever see growth again
with the SNP consortium and human genome project in
play? I used to be bullish on INCY, can someone remind
me why this company is a gem?