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Advanced Medical Isotope Corporation Message Board

  • wise4stocks wise4stocks Mar 6, 2013 1:23 PM Flag

    ADMD's game-changing technology (from headlines)

    A complete analysis of ADMD's products would take an article in itself. That being the case, let's focus on ADMD's potential game-changing technology known as brachytherapy and Radiogel. The company's unique take on brachytherapy is an advanced cancer treatment where radioactive seeds or medium are placed in or near a tumor. Once implanted these localized seeds give a high radiation dose to the tumor. While this technology is quite successful, it does have problems. The seeds' radioactivity can persists for weeks and will irradiate healthy surrounding tissues along with the cancer. This is where Radiogel comes into play.

    Radiogel is best described as a water-based injectable biodegradable polymer that delivers yttrium-90 microspheres (seeds) directly into tumor tissues. The solution warms to body temperature upon injection and then polymerizes into a lattice that traps the radioactive microspheres in place. At this point is where the seeds go to work by irradiating cancer cells within the localized area. The key to Radiogel systems is that very little radiation escapes. Radiogel may also be administered transdermally or intraoperatively when treating solid tumors that cannot be removed safely by surgery. This means the treatment can be applied to a variety of conditions such as inoperable liver cancer, brain tumors, head and neck tumors, kidney tumors, and pancreatic cancer.

    In February 2011 ADMD obtained the exclusive license to eight patents for the Radiogel technology. As part of the license, ADMD will have the right to make, have made, use, and sell the Radiogel system. The company's goal is to manufacture Radiogel in Washington State by building a new facility in Richland, Washington. As exciting as this technology is, it is still early in its development. On February 5, 2013, ADMD submitted data on Radiogel to the FDA and requested a collaborative meeting. This action would represent the initial step in the FDA's pre-market review process of the Radiogel.

    Sentiment: Strong Buy

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