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StemCells Inc. Message Board

  • stem_cur stem_cur Sep 7, 2012 3:17 PM Flag


    Go to the OC REGISTER and read the article....." UCI stem-cell researchers to share in $37 million state awards"

    The team includes Henry Klassen, a UC Irvine associate opthalmology professor, as well as researchers from UC Santa Barbara and Cedars-Sinai Medical Center. The UC Irvine

    The disease is often diagnosed when patients are in their teens or young adulthood, and

    “First there’s night blindness,” Klassen said. “Then tunnel vision, and eventually,

    The treatment he’s developing relies on retinal stem cells that have matured enough to be specific to eye function. In previous testing, it has restored vision in rats.

    The funding will allow more preliminary work in preparation for human testing. Food and Drug Administration approval, Klassen said, could come as soon as the end of next

    The second award, for $20 million, will go to neurobiologists Frank LaFerla and Mathew Blurton-Jones, of the institute UCI MIND, and StemCells Inc. of Newark, Calif., to further develop a treatment to improve memory in Alzheimer’s patients using human neural

    In July, UC Irvine reported that the treatment improved memory in mice with brain

    “The stem cells were releasing a factor, and that factor was sort of acting like a fertilizer for the brain, and causing the surviving neurons to put out more connections,” LaFerla said Thursday. “So it was enhancing the health of the surviving neurons in the brain.”

    The award will allow further tests on mice bred to model Alzheimer’s; at the end of the four-year testing period, LaFerla said, the research team will file an application to the Food and Drug Administration in preparation for human trials of the treatment.

    The human neural stem cells, derived from donated brain tissue of surgically aborted

    Stem cells have the potential to transform into a variety of cell types based on cues they receive from the body, and have touched off a surge of research to treat a variety of

    Each of the three UCI scientists involved in the two projects also are part of the Sue &

    The awards came from the California Institute for Regenerative Medicine, or CIRM, a

    The awards were part of $63 million worth in funds given to institutions and companies

    The UCI campus has received a total of $96.2 million from CIRM.

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