New Assembly Method Published for Rapid and Automated Genome Sequencing Using PacBio RS
The newly published Nature Methods paper "describes the hierarchical genome assembly process (HGAP) and demonstrates the method for efficient, automated de novo assembly from genomic DNA to a finished genome sequence for several microorganisms and a human bacterial artificial chromosome (BAC) clone." This is extremely exciting, especially that no hybrid-assembly approach is needed.
"This approach can close the large gap that currently exists between 'draft' and high-quality 'finished' genomes," said Jonas Korlach, senior author on the paper and Chief Scientific Officer at Pacific Biosciences.
I expect that the this news could generate lots of interests in the third-gen sequencing field both academic and industrial. Way to go PacBio.