IMHO the next catalysis will be a dilution by introducing more shares into float, the one approved in December shareholder's meeting, it could happen any day from now until June and it won't be a pretty picture for few days at the least.
remember current trail is for 26 weeks and nothing is going to come out sooner then that, and it is the only source of good news at this point unless some big pharma place a bid on Prana.
The last dilution didn't hurt the stock price too much. The company handled it reasonably well. It kept the stock price from rising as fast as some of us would like, but it did rise, and like the South it will rise again. It won't take much buying to kick this back up over 3 bucks again.
As we get closer to some pivotal news, the demand for the stock will pick up, so the company may be able to place some large blocks of that stock. It may not all be sold at-the-market. Even if it is, there was ample demand for it in the recent past, and there certainly will be now. Load up if you can.
As this year rolls along, I expect PBT434 to garner more attention. Lots of potential news out there.