I'm a critical care doctor and deal with multi drug resistant infections all the time. Looked at their p2 and lab data and the lead antibiotic enavercycline looks great. It has activity against all the major drug resistant bacteria except pseudomonas. In the P2 it was equally effective to meropenem which is one of the most potent IV antibiotics. Tetracyclines are very safe antibiotics and don't have major toxicities such as kidney failure that limit their use. The fact that enavercycline can likely also be given orally makes this a potential blockbuster drug. If the P3 comes in showing effciacy, this could be a billion dollars annual worldwide sales. The problem for the last 4 decades was that tetracyclines were so complex they could not be synthesized and modified from scratch, they had to be generated from tetracycline producing bacteria. TTPH has patented a chemical process that allows them to build tetracyclines from scratch and modify them to overcome current bacterial resistance, they have made over 1000 different variations in the lab and took the best compound to be their lead product. They have 2 or 3 more on the way in the pipeline. This stock is way under the radar if you look at the anemic volume, but someone is buying.
Thanks Doc.............confirms other sources. Who knows when it will get taken out at a premium considering its drug discovery and developing product lines. I've been accumulating since it was seven last spring.
Good summary, thank you. I am going to hold this one for some time....I have a very, very, good position in my IRA and I have years to hold it....hoping it makes it to the bigs like you postulate...
Thanks doc for taking your valuable time again to post and to help us understand the science behind this company, and why it is probably moving like it has been for the last few months. We sincerely appreciate it and I believe I can speak for all of the longs here. Your early analysis was one of the major reasons I got in, albeit late,,at 9 but so thankful that I did. Please keep posting when you can as events arise either pro or con as we,really value your input! Thanks again....Happy New Year to you.
I'm also a doc and love this drug but I am out today. I've doubled my money here in a few months and I am getting dizzy. I'll be back I closer to approval or if it falls.
Good job then doc and anytime you double your money it's a homerun.
For me...I'm holding TTPH large as I think the future is very bright for this one.
Since I sold a nice position in PCYC at $18 after buying it at $14 (now $129), I'm
not selling a share of this one until we hit that 800 mil market cap at the very least.
I wish you docs would take a look at IDRA and let us know your opinions.
It has really run since November and the Harvard docs seem to be involved as
do the Baker Bros. who got into PCYC very early and very large, and they still hold that
name without sales as far as I can tell. If this is the next homerun I'd like to know
but already own it large from $4.50. Institutions have been piling into it. Take a