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Celgene Corporation Message Board

broad_and_south 12 posts  |  Last Activity: Jun 29, 2016 8:16 PM Member since: Oct 18, 2007
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  • Reply to

    Way oversold...my lord.

    by sdfgtyuhjiko Jun 29, 2016 3:44 PM
    broad_and_south broad_and_south Jun 29, 2016 8:16 PM Flag

    Traders use the word "oversold" in the wrong context. If there is no change in the fundamentals, meaning intrinsic valuation, and the stock goes down, it is oversold.

    However if there is a significant change in the fundamentals, a sell off happens to find the new trading level. In the case of ESPR, the fundamentals have changed.

  • Reply to

    My Prediction

    by bull_dot_com Jun 22, 2016 4:35 PM
    broad_and_south broad_and_south Jun 23, 2016 7:12 AM Flag

    Are you asleep? Steve Jobs was great at AAPL. But Musk created Paypal, TSLA, SCTY, and SpaceX. He is a wunderkind of Jobs's proportion.

    But Musk takes a step backwards with this SCTY deal.

  • broad_and_south by broad_and_south May 31, 2016 10:08 AM Flag

    Since Saturday morning, the posts on the MB have been over the top on the price ICPT will rise once the markets opened up on Tuesday. Some even had a GILD deal ready to be announced on Monday. I was chastised for offering a $145-$150 price today. I will probably not be too far off.

    I think ICPT has a bright future but it will take longer to manifest itself. Once GILD bought into Nimbus, you knew that a major liver disease company was out of play. But the real issue is Hillary and her desire to get drug prices down. VRX and Martin Shrikeli did a lot to cause this problem. ICPT's NASH potential is immature but promising, They have $700k in the bank to fund the trial. ICPT will not sell at a Hillary-degraded price. They are smart to wait. Buyers will not offer big prices until the political overhang is gone.

    All this played out last week with very poor trading in a stock about to receive FDA approval. ICPT will trade in will defined bounds until something happens to change the value of the company.

  • Reply to

    GILEAD and Nimbus Apollo

    by gmrowe May 30, 2016 5:22 AM
    broad_and_south broad_and_south May 30, 2016 11:55 AM Flag

    I think a target like REGN will fill the bill. They have growing earnings. No product overlap so the FTC will not stop the merger.

    Of course there are others, but this comes to mind.

  • Reply to

    GILEAD and Nimbus Apollo

    by gmrowe May 30, 2016 5:22 AM
    broad_and_south broad_and_south May 30, 2016 11:39 AM Flag

    The last ER for GILD was bad. The stock is in portfolios that demand performance now. Wall Street is dysfunctional this way. ICPT NASH is a few years away and an orphan indication for PBC will not move the needle. I think the Nimbus acquisition was a "tell."

  • Reply to

    GILEAD and Nimbus Apollo

    by gmrowe May 30, 2016 5:22 AM
    broad_and_south broad_and_south May 30, 2016 10:58 AM Flag

    Many people misread GILD's need to acquire. Yes they do need to buy an asset, but it must be immediately accretive to sales and earnings growth rate. Like it or not, this is the Wall Street game. In baseball, teams will acquire a hot pitcher in July or August to make a run for the pennant. This is GILD.

    I viewed the Nimbus acquisition as drafting an 18 yo into the farm team. It will take years for Nimbus to commercialize a NASH product. It would seem that GILD made a run at ICPT and backed out when the price got too steep. They then went with Nimbus.

    A new drug in a new indication is not a done deal after a successful P3 and FDA approval. There is insurance coverage, foreign markets, and side effects not seen during trials. I would rate ICPT as a promising AAA baseball player who is called up during a pennant race to fill a gap perhaps only for one start.

    Getting back to your question: GILD does not need two solutions for NASH.

  • broad_and_south broad_and_south May 28, 2016 1:47 PM Flag

    If I were to speculate on the obviously very good factors, the numbers would be high.

    There was much more trading activity before the AdCom in early April. Last week was distinctly blah. No drama in the price action at a time when there should be is very odd. It means everything is baked in.

    I think the future is very bright for ICPT. But when Hillary peed on the entire sector, valuations took a nosedive.

  • broad_and_south broad_and_south May 28, 2016 12:58 PM Flag

    I think it will push to $145-$150. The market already knew about the FDA decision and the trading showed it.

    Last year at this time, RCPT was bought out by CELG at a price most longs thought was low. ICPT is further along as they will soon have revenues. My point is that only a bidding war will cause the price to go to the moon. If that were to happen, we would have seen it already. In other words, last night's announcement was not a surprise. All the buyout candidates already knew about the approval through NDA.

  • broad_and_south by broad_and_south May 20, 2016 7:15 AM Flag

    MNKD only has 250 people and is still a developmental stage company. Its plant in Danbury is way too large for the market at this time. Cash burn rate is $10-12 mln/mo. Do some back of the envelope calculations and one can estimate they need 100k users just to be cash flow neutral. The existing base is 2.5-3k users. Mike Castanga is an energetic guy and will do well. But to get to 100k users, it will take years.

    MNKD probably needs $200-300 mln to get to cash flow neutrality over the next 2-3 years. Partnerships will bring in some cash. So will product sales. But there is a funding gap that will rear its ugly head.

    The best hope is that Afrezza goes viral in the diabetic community.

  • Reply to

    Elephant in the room.

    by surplus.value May 19, 2016 9:10 PM
    broad_and_south broad_and_south May 19, 2016 9:38 PM Flag

    I think partnerships is one source.

    But they also voted in a proposal to increase share count to 700 mln.

  • Reply to

    Share holder's meeting

    by broad_and_south May 19, 2016 4:27 PM
    broad_and_south broad_and_south May 19, 2016 9:36 PM Flag

    Titrating Afrezza should not be a mystery given all the clinical trials performed with the product. It is after all, insulin in a different carrier. Having only 20k try the product in the first year is a problem. With over 1 mln Type 1 DB in the US, you would think first year would be six figures. I think SNY gave up after 6 months and quietly told their reps to hump something else. Like Tuoujeo.

  • broad_and_south by broad_and_south May 19, 2016 4:27 PM Flag

    This year's ASM was not as upbeat as last year's. But it was not down. Everyone one knew MNKD has one more chance to take the #$%$ down the ice and score.

    The most patients SNY got was 2,500 at one time. This is from the entire US. Drop outs killed the program.

    The huge amount of inventory sold to SNY will mostly be scrapped. More losses added to the $60 mln already on the books. It turns out this debt is secured by MNKD's Valencia's building.

    SNY used its very large sales and marketing staff to cover the diabetic waterfront. Castanga will only initially have 40 reps calling on endos. Type 2 will be put on the back burner. Primary care also.

    The big question is will Mike Castanga run into the same problems SNY encountered? My take is that he is far more focused than SNY ever was. He has 1 year's data to work from. But even he said drug relaunches rarely go well. Because he signed onto MNKD, he must believe this does not apply to Afrezza.

    MNKD needs 12 months to prove weather they can make a go of Afrezza. To do so requires more cash, probably another $50 mln.

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